Could you elaborate on what you mean re: convincing regulatory bodies? I'm not used to working in a highly-regulated environment. Why are they involved? For certification of the lab?
EDIT> I mean involved w.r.t plate sealers/unsealers, not more generally.
If you want CLIA lab certification, there are a number of rules surrounding cross contamination, which not sealing a plate of samples properly might be a red flag.
EDIT> I mean involved w.r.t plate sealers/unsealers, not more generally.